CERULOPLASMIN

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CLINICAL SIGNIFICANCE
Ceruloplasmin is a plasma ferroxidase protein that functions as a copper transporter, which normally binds 90% of the copper present in plasma. Incorporation of the copper into the structure occurs during the synthesis of Ceruloplasmin at the hepatocytes. Moreover Ceruloplasmin has a catalytic function in the oxidation of iron, polyamines, catecholamines and polyphenols. It is also an acute phase reactant whose serum levels rise significantly at acute inflammation, myocardial infarction, infections and tumors. Lower than normal Ceruloplasmin levels are noted at Menkes disease, Wilson disease, malnutrition, malabsorption, nephrosis. Increased Ceruloplasmin levels are observed at pregnancy, lymphoma and rheumatoid arthritis.
CHARACTERISTICS

Form: Liquid ready-to-use
Shelf life: 12 months @ 2-8 C
On-Board Stability: 60 days
Sample: Serum or heparinised, EDTA-plasma
Detection limit: 0.1 mg/dL
Linearity: 5.5-120 mg/dL


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MEDILYZER
EX-OLYMPUS
GENERAL PURPOSE
SIEMENS ADVIA
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2x60 Tests
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2x150 Tests