APOLIPOPROTEIN B
apo B


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CLINICAL SIGNIFICANCE
Elevated levels are observed in type IIa, IIb, IV and V types of lipoproteinemia, â-apolipoproteinemia (normal LDL-C, high LDL-Apo-B), early coronary disease, diabetes, hypothyroidism, nephrotic syndrome, kidney failure, hepatic disease, Cushing syndrom, dysglobulinemia, porphyria, pregnancy, anorexia nervosa, pituitary dwarfism, child hypercalcemia, sphingolipodystrophies, Werner syndrom, emotional charging-stres.

Apo-B deficiency is observed at a-lipoprotein deficiency (Tangler’s disease), heterozygous hypo-â-lipoproteinemia, lipoproteininc lipase cofactor deficiency (Apo C-II), hyperthyroidism, malnutrition, hyperthyroidism, malnutrition, intestinal malabsorption, chronic anemia, severe hepatocellular dysfunction, Reye syndrome, joint inflammations, chronic lung conditions, myeloma, or weight loss.

Apo-B is absent in cases of a-â-lipoproteinemia and homozygous â-hypolipoproteinemia. In such cases, measurement of Apo-B concentration in serum acts as confirmation.
CHARACTERISTICS

Form: Liquid ready-to-use
Shelf life: 12 months @ 2-8 C
On-Board Stability: 30 days
Sample: Serum or plasma with EDTA
Detection limit: 1 mg/dL
Linearity: 4-250 mg/dL


Packaging
For Use On
MEDILYZER
EX-OLYMPUS
GENERAL PURPOSE
SIEMENS ADVIA
Packaging
6x30 Tests & 6x100 Tests
4x50 Tests & 4x100 Tests
R1 3x100, R2 75
4x80 Tests & 4x200 Tests