URIC ACID

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CLINICAL SIGNIFICANCE
Elevated uric acid can be due to purine-rich diet, severe exercise, gout, renal failure, leukemia, multiple myeloma, polycythemia, lymphoma, other disseminated neoplasms, toxemia of pregnancy, psoriasis, glycogenosis Type I, Lesch-Nyhan syndrome, Down’s syndrome, polycystic kidney disease, chronic lead nephropathy. Uric acid is also increased in obesity, hyperlipidemia, hypertension, atherosclerosis, diabetes mellitus, ethanol consumption, hypoparathyroidism, acromegaly, sarcoidosis and liver disease, gross tissue destruction, excessive nucleoprotein metabolism (e.g. myeloid leukemia, pernicious anemia, strychnine poisoning). Acute (sometimes dangerous) elevation follows treatment of leukemia with cytotoxic drugs.

A reduction of uric acid in serum can be observed at Wilson’s disease, Fanconi syndrome, Hodgkin’s disease, multiple myeloma, bronchogenic carcinoma, xanthinuria, SIADH, deficiencies of adenosine deaminase, purine, nucleoside phosphorylase or low purine diet.
CHARACTERISTICS

Form: Liquid, ready-to-use
Shelf life: 18 months @ 2-8 C
On-Board Stability: 30 days
Sample: Non hemolysed serum or plasma
Detection limit: 0.5 mg/dL
Linearity: 0.5–30 mg/dL


Packaging
For Use On
MEDILYZER
EX-OLYMPUS
GENERAL PURPOSE
SIEMENS ADVIA
Packaging
6x110 Tests
4x200 Tests & 4x500 Tests
R1 2x125 mL, R2 2x125 mL
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