g GLUTAMYL TRANSFERASE
gGT


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CLINICAL SIGNIFICANCE
L-Gamma Glutamyl Transferase (γ-GT) is a liver enzyme catalyzing the transfer of amino acids from one peptide to another. γ-GT is present in all cells of the body except those in muscle. The enzyme present in serum appears to originate from the hepatobiliary system. Elevated levels in serum may indicate an abnormality in liver caused by congestive heart failure, cholestasis, cirrhosis, necrosis of the liver, liver tumors, hepatitis, intrahepatic or posthepatic biliary obstruction. It is more sensitive than alkaline phosphatase in detecting obstructive jaundice, cholangeitis, and cholecystitis and its rise occurs earlier and persists longer. γ-GT is also increased in acute or chronic pancreatitis, infectious hepatitis, fatty liver, in patients receiving anticonvulsant drugs such as phenytoin and phenobarbital. γ-GT plays a role in the detection of alcoholism, alcoholic liver damage and in monitoring alcohol abstinence.

γ-GT is a useful indicator for the pancreatic or liver cancer, because its levels reflect the extend of the disease and the response to the treatment.
CHARACTERISTICS

Form: Liquid, ready-to-use
Shelf life: 24 months @ 2-8 C
On-Board Stability: 60 days
Sample: Fresh, non hemolyzed serum or plasma with up to 1 mg/mL EDTA
Detection limit: 0 U/L
Linearity: 3–1000 U/L


Packaging
For Use On
MEDILYZER
EX-OLYMPUS
GENERAL PURPOSE
SIEMENS ADVIA
Packaging
6X100 Tests & 6X200 Tests
4X100 Tests & 4X500 Tests
R1 3x120 mL, R2 90 mL & R1 2x125 mL, R2 2x125 mL
4X200 Tests & 4X700 Tests