ETHANOL

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CLINICAL SIGNIFICANCE
The measurement of ethanol in blood is important for the determination of drunkenness or at toxicological tests. Ethanol is diluted in water, absorbed quickly and infiltrated in all the tissues of the organism. The elimination of alcohol begins at the stomach and the rate of this process is proportional to the time it remains there. The most important tissue, which contains enzymes suitable for the metabolism of ethanol, is the liver that is influenced by alcoholism. In a few hours all the ethanol is degraded at quiescent products. When large amounts of ethanol are consumed for a long period of time liver activates specific enzymatic systems to eliminate the large quantity. This fact leads to the formation of toxic metabolites, which destroy the hepatocytes. Moreover the protective mechanisms (antioxidant defence) are exhausted and as a consequence the organism is more vulnerable at toxins and factors causing cancer. The final result is inflammation and necrosis of the hepatocytes.
CHARACTERISTICS

Form: Freeze-dried
Shelf life: 18 months @ 2-8 C
On-Board Stability: 7 days
Sample: Non hemolyzed serum, plasma, or venous whole blood with heparin, citrate or oxalate
Detection limit: 0.4 mg/dL
Linearity: up to 300 mg/dL


Packaging
For Use On
MEDILYZER
EX-OLYMPUS
GENERAL PURPOSE
SIEMENS ADVIA
Packaging
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10x33 Tests
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