CREATININE

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CLINICAL SIGNIFICANCE
Creatinine is a metabolic product of creatine phosphate in muscle and it is usually produced at a fairly constant rate by the body. Measuring serum creatinine is the most commonly used indicator of renal function. It is useful in the evaluation of kidney glomerular function and in monitoring renal dialysis. In post renal conditions where obstruction of the urine flow is present, e.g. malignancy, nephrolithiasis and prostatitis both plasma and urine creatinine will be increased. Serum creatinine varies with the subject’s age, body weight and sex.

Increased levels of creatinine are observed in acute or chronic renal function deficiency of any cause, in active acromegaly, gigantism, hyperthyroidism and diet rich in meat. Low levels of creatinine are observed during pregnancy, (especially in the 1st and 2nd semester), in cases of increased muscle mass loss, in amputees and elderly people.
CHARACTERISTICS

Form: Liquid, ready-to-use
Shelf life: 18 months @ 2-8 C
On-Board Stability: 7 days
Sample: Serum or plasma with heparin or fluoride
Detection limit: 0.01 mg/dL
Linearity: up to 30 mg/dL


Packaging
For Use On
MEDILYZER
EX-OLYMPUS
GENERAL PURPOSE
SIEMENS ADVIA
Packaging
6X60 & 6X180 Tests
4x500 Tests
R1 2x125 mL, R2 2x125 mL
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