CREATINE KINASE
CK


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CLINICAL SIGNIFICANCE
Creatine Kinase is an enzyme that catalyzes the conversion of creatine to phosphocreatine, by converting ATP to ADP. Increased CK levels are observed at trauma, surgery, myocardial infarction, loss of blood supply to any muscle, myopathic disorders and muscular dystrophies of any type, Reye’s syndrome, malignant hyperpyrexia, prolonged hypothermia, hypothyroidism, infectious diseases (e.g. typhoid fever), arrhythmias (infrequently), direct-current countershock, congestive heart failure, tachycardia, pulmonary embolism, tetanus, generalized convulsions, extensive brain infarction. Lower than normal levels probably have no meaning but reflect either small muscle mass, sedentary lifestyle or both. Bedrest even overnight can lower CK activity by 20% or more.
CHARACTERISTICS

Form: Liquid, ready-to-use
Shelf life: 12 months @ 2-8 C
On-Board Stability: 21 days
Sample: Non hemolyzed serum, or plasma with EDTA or heparin
Detection limit: 1 U/L
Linearity: 5-2000 U/L


Packaging
For Use On
MEDILYZER
EX-OLYMPUS
GENERAL PURPOSE
SIEMENS ADVIA
Packaging
6x50 Tests & 6x200 Tests
4x50 Tests & 4x200 Tests
R1 3x120 mL, R2 90 mL
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