CHOLESTEROL

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CLINICAL SIGNIFICANCE
Cholesterol is found in high concentrations in tissues which either produce more or have more densely-packed membranes, for example, the liver, spinal cord, brain and also in atheromas. Cholesterol is best known for the association of cardiovascular disease to various lipoprotein cholesterol transport patterns and to high levels of cholesterol in the blood.

Increased levels of cholesterol are found in familial or polygenic hyperlipoproteinemia type IIa and IIb, familial combined hyperlipidemia, intra and extra hepatic cholestasis, glomerulonephritis, nephrotic syndrome, chronic renal failure, malignant neoplasms of the pancreas and prostate, hypothyroidism, ischemic heart disease, diabetes, dysglobulinemia, anorexia nervosa. Reduced levels of cholesterol are observed in a-lipoprotein deficiency, hypo a- and â-lipoproteinemias, hepatocellular necrosis, malignant neoplasm of the liver, hyperthyroidism, malabsorption, malnutrition, megaloblastic anemias, sideroblastic anemia, thalassemia, severe acute illness, extensive burns, rheumatoid arthritis, intestinal lymphangiectasia.
CHARACTERISTICS

Form: Liquid ready-to-use
Shelf life: 18 months @ 2-8 C
On-Board Stability: 30 days
Sample: Serum or plasma with heparin or EDTA
Detection limit: 0 mg/dL
Linearity: 6–600 mg/dL


Packaging
For Use On
MEDILYZER
EX-OLYMPUS
GENERAL PURPOSE
SIEMENS ADVIA
Packaging
6x200 Tests
4x500 Tests
R1 4x125 mL & R1 1000 mL
4x675 Tests