ASPARTATE AMINOTRANSFERASE
AST GOT


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CLINICAL SIGNIFICANCE
Aspartate Aminotransferase (AST) is similar to alanine aminotransferase (ALT) in that it is another enzyme associated with liver parenchymal cells. It is also present in red blood cells and cardiac muscle. Both enzymes are good indicators of liver damage. The ratio AST/ALT sometimes can help to determine whether the liver or another organ has been damaged. The AST/GOT activity is increased in liver cell necrosis or injury of any cause, including cholestatic and obstructive jaundice, alcoholic or viral or chronic hepatitis, hepatic metastases and hepatoma, infectious mononucleosis. Also in necrosis or trauma or inflammation of cardiac or skeletal muscle, acute myocardial infarction, severe exercise, extensive burns, Forbs disease, hypothyroidism, intestinal infarction, extrahepatic cholestasis, progressive muscular dystrophy, dermatomyositis, acute pancreatitis, haemolytic disease.
CHARACTERISTICS

Form: Liquid ready-to-use
Shelf life: 18 months @ 2-8 C
On-Board Stability: 30 days
Sample: Non hemolyzed serum or heparinized plasma
Detection limit: 2 U/L
Linearity: 6-800 U/L


Packaging
For Use On
MEDILYZER
EX-OLYMPUS
GENERAL PURPOSE
SIEMENS ADVIA
Packaging
6x90 Tests
4x200 Tests & 4x500 Tests
R1 3x120 mL, R2 90 mL
4x270 Tests & 4x670 Tests
Calibrator
Calibration Factor or Medi-cal multi-test calibrator Freeze-Dried 12x5 mL.
Control 1
Clinical Chemistry Control Level I, Freeze-Dried 12x5 mL.
Control 2
Clinical Chemistry Control Level II, Freeze-Dried 12x5 mL.